Research — Developmental Biology

Fourth year

(M70 900)
Cross-listed with L41 (Bio) 590

Irving Boime, PhD
3rd Floor McDonnell Sciences Building
Secretion, targeting and structure-function of the human placental and pituitary glycoprotein hormones.

Douglas F. Covey, PhD
3rd Floor McDonnell Sciences Building
Medicinal chemistry of steroids.

Aaron DiAntonio, MD, PhD
6301, 4515 McKinley Research Building
Neurodevelopment, neurodegeneration, and axon regeneration in Drosophila and mouse.

Gregory A. Grant, PhD
3rd Floor North Building
Mechanism of allosteric regulation in enzymes.

Shin-Ichiro Imai, MD, PhD
Room 362A McDonnell Medical Sciences Building
Molecular mechanisms of aging and longevity in mammals, particularly focusing on the tissue-specific functions of the mammalian NAD-dependent deacetylase Sirt1 and the physiological significance of systemic NAD biosynthesis mediated by Nampt (nicotinamide phosphoribosyltransferase) in an intimate connection between metabolism and aging.

Kerry Kornfeld, MD, PhD
3rd Floor Cancer Research Building
Signal transduction during development. Zinc metabolism. Aging.

Kristen Kroll, PhD
Room 320, McDonnell Sciences Building
Transcriptional networks that regulate the formation of neurons in early embryos and embryonic stem cells.  Role of chromatin regulatory complexes in controlling pluripotency and differentiation.

Craig Micchelli, PhD
Room 328, McDonnell Sciences Building
Our lab studies the regulation of stem cell biology in development, homeostasis, and disease.

Kelly Monk, PhD
360 McDonnell Sciences Building
Mechanisms of myelin formation, demyelination, and remyelination in zebrafish and mouse.

Samantha Morris, PhD
3316, 4515 McKinley Research Building
Stem Cell and Developmental Biology. Our research focuses on dissecting the gene regulatory networks that define cell identity, using the developing embryo and tissue regeneration as a guide to engineer fate in vitro.

Jeanne M. Nerbonne, PhD
9900 CSRB
Structure, function and regulation of voltage-dependent ion channels in the cardiovascular and nervous systems.  Regulation of membrane excitability in health and disease.

David M. Ornitz, MD, PhD
3rd Floor South Building
Regulation of cardiovascular, lung, skeletal, and inner ear development, injury response, and regeneration by Fibroblast Growth Factors.

John H. Russell, PhD
3rd Floor McDonnell Sciences Building
Mechanisms of lymphocyte-mediated inflammation and pathogenesis in the central nervous system.

Lila Solnica-Krezel, PhD
3911A South Building
Genetic Regulation of Vertebrate Embryogenesis. Genetic mechanisms that regulate cell fates and movements during early vertebrate development using forward and reverse genetics in the zebrafish model and human embryonic stem cells.

Andrew Yoo, PhD
361E, McDonnell Sciences Building
Cell fate control by microRNAs. Neuronal reprogramming to generate human neurons. Chromatin controlling factors and genetic pathways that regulate neurogenesis.

Zachary Pincus, PhD
5304, 4515 McKinley Research Building
Inter-individual variability in aging and lifespan. Developmental origins of longevity and adult health. Quantitative microscope and image analysis of C. elegans.