Research — Surgery

L. Michael Brunt, MD
1160 Northwest Tower, Barnes-Jewish Hospital
Minimally invasive surgery, including endocrine applications. Minimum rotation length: four weeks. Under the auspices of the Washington University Institute for Minimally Invasive Surgery (WUIMIS), a number of surgeons are investigating the physiologic consequences of laparoscopic surgery and new applications for procedures and technologies. Dr. Brunt is currently investigating clinical outcomes of various laparoscopic surgical procedures, laparoscopic hiatal hernia surgery and adrenal surgery, and is carrying out education related research of skills training for senior medical students planning to enter a surgical internship.

Division of Plastic and Reconstructive Surgery
660 S. Euclid, Box 8238
The Division of Plastic Surgery offers many opportunities for research projects on various topics related to plastic surgery.  A project will be designed with the student prior to his/her rotation on plastic surgery so that all of the materials and methods will be available at the beginning of the rotation. The basic science laboratories investigate primarily nerve injury and regeneration including nerve transplantation. The student will be encouraged to design and complete his/her own research study during the elective. Minimum rotation length is six weeks. The research rotation can be conducted in the plastic surgery laboratories under the direction of Drs. Moore, Snyder-Warwick, Wood or Mackinnon.
Ongoing projects include:
(1) influence of growth factors and blood flow on nerve regeneration;
(2) neural tissue engineering;
(3) diagnostic potential of biomarkers to identify nerve injury; and
(4) investigation of glial cells at the neuromuscular junction during development, maintenance, aging, and following nerve injury.

Additional clinical and educational research opportunities in various fields of plastic surgery are available with Drs. Fox, Myckatyn, Patel, Tung, and Woo.

These various projects include:
(1) in vivo tissue generation and tissue differentiation;
(2) the mechanical, structural and biochemical effects of stress on scar tissue maturation;
(3) in vivo anatomy of craniofacial deformities;
(4) outcome analysis of methods of cleft lip and palate management;
(5) breast reconstruction (3D imaging of breasts after cosmetic or reconstructive surgery, interpretation of angiograms of the breast to measure nipple perfusion);
(6) use of nerve transfer to improve hand function in patients with cervical spinal cord injury/quadriplegia; and
(7) surgical education (specifically web-based multi-media strategies for peripheral nerve surgery education).